Search results for " ascending thoracic aortic aneurysm"

showing 3 items of 3 documents

Difference in hemodynamic and wall stress of ascending thoracic aortic aneurysms with bicuspid and tricuspid aortic valve.

2012

The aortic dissection (AoD) of an ascending thoracic aortic aneurysm (ATAA) initiates when the hemodynamic loads exerted on the aneurysmal wall overcome the adhesive forces holding the elastic layers together. Parallel coupled, two-way fluid–structure interaction (FSI) analyses were performed on patient-specific ATAAs obtained from patients with either bicuspid aortic valve (BAV) or tricuspid aortic valve (TAV) to evaluate hemodynamic predictors and wall stresses imparting aneurysm enlargement and AoD. Results showed a left-handed circumferential flow with slower-moving helical pattern in the aneurysm's center for BAV ATAAs whereas a slight deviation of the blood flow toward the anterolater…

Aortic valveMalemedicine.medical_specialtyFluid–structure interaction Aortic dissection Ascending thoracic aortic aneurysm Bicuspid aortic valveBiomedical EngineeringBiophysicsHeart Valve DiseasesAorta ThoracicThoracic aortic aneurysmArticleAortic aneurysmBicuspid aortic valveBicuspid Aortic Valve DiseaseInternal medicinemedicine.arteryCoronary CirculationAscending aortamedicineThoracic aortaHumansOrthopedics and Sports Medicinecardiovascular diseasesAgedAortic dissectionAortabusiness.industryRehabilitationHemodynamicsModels CardiovascularMiddle Agedmedicine.diseaseElasticityAortic Aneurysmmedicine.anatomical_structureAortic ValveCardiologycardiovascular systemFemaleTricuspid ValvebusinessJournal of biomechanics
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Regional variation of wall shear stress in ascending thoracic aortic aneurysms.

2014

The development of an ascending thoracic aortic aneurysm is likely caused by excessive hemodynamic loads exerted on the aneurysmal wall. Computational fluid-dynamic analyses were performed on patient-specific ascending thoracic aortic aneurysms obtained from patients with either bicuspid aortic valve or tricuspid aortic valve to evaluate hemodynamic and wall shear parameters, imparting aneurysm enlargement. Results showed an accelerated flow along the outer aortic wall with helical flow in the aneurysm center for bicuspid aortic valve ascending thoracic aortic aneurysms. In a different way, tricuspid aortic valve ascending thoracic aortic aneurysms exhibited normal systolic flow without su…

Computational fluid dynamics ascending thoracic aortic aneurysm bicuspid aortic valve wall shear stress hypertensionAortic valvemedicine.medical_specialtyAortabusiness.industryMechanical EngineeringSettore ING-IND/34 - Bioingegneria IndustrialeHemodynamicsGeneral Medicinemedicine.diseaseThoracic aortic aneurysmSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di MacchineBicuspid aortic valveAneurysmmedicine.anatomical_structuremedicine.arteryInternal medicinecardiovascular systemmedicineCardiologyShear stresscardiovascular diseasesbusinessHelical flowProceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
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Fiber Micro-Architecture in the Longitudinal-Radial and Circumferential-Radial Planes of Ascending Thoracic Aortic Aneurysm Media.

2013

It was recently demonstrated by our group that the delamination strength of ascending thoracic aortic aneurysms (ATAA) was lower than that of control (CTRL, non-aneurysmal) ascending thoracic aorta (ATA), and the reduced strength was more pronounced among bicuspid (BAV) vs. tricuspid aortic valve (TAV) patients, suggesting a different risk of aortic dissection for BAV patients. We hypothesized that aortic valve morphologic phenotype predicts fiber micro-architectural anomalies in ATA. To test the hypothesis, we characterized the micro-architecture in the longitudinal-radial (Z-RAD) and circumferential-radial (Θ-RAD) planes of human ATA tissue that was artificially dissected medially. The ou…

MaleAortic valve030204 cardiovascular system & hematology0302 clinical medicineThoracic aortaOrthopedics and Sports MedicineHuman ascending thoracic aortic aneurysmAortic dissection0303 health sciencesbiologyDissectionRehabilitationAnatomyMiddle AgedTunica intimaBiomechanical Phenomenamedicine.anatomical_structureAortic Valvecardiovascular systemCardiologyFemaleCollagenTunica Mediamedicine.medical_specialtyMicro-architectureMaterials scienceAortic RuptureBiomedical EngineeringBiophysicsDissection (medical)Multi-photon microscopyThoracic aortic aneurysmArticle03 medical and health sciencesInternal medicinemedicine.arterymedicineHumansAortic rupture030304 developmental biologyAnalysis of VarianceAortic Aneurysm ThoracicPhenolmedicine.diseaseElastinAortic DissectionMicroscopy Fluorescence Multiphotonbiology.proteinTunica IntimaElastin
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